Bendamustine hydrochloride

Product Details:

EINECS No 222-412-0
Smell Odorless,
Loss on Drying ≤0.5%
Structural Formula C1=NC2=C(C=CC(=C2)Cl)C(OC3=CC=C(C=C3)Cl)=C1Cl
Poisonous YES,
Solubility Freely soluble in water slightly soluble in ethanol
Color White to off-white,
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Bendamustine hydrochloride Product Specifications

Shelf Life 24 months
CAS No 3543-75-7
Storage Store at room temperature (15°C to 30°C) away from light and moisture
Melting Point 153°C to 156°C
Ph Level Neutral (5–7 in aqueous solution)
HS Code 29339980
Molecular Weight 394.72 g/mol
Molecular Formula C16H21Cl2N3O2.HCl
Taste Bitter
Grade Pharmaceutical Grade
Particle Size 50–100 micron
Appearance White to off-white crystalline powder
EINECS No 222-412-0
Chemical Name 1H-Benzimidazole-2-butanoic acid 5-(bis(2-chloroethyl)amino)- monohydrochloride
Purity(%) 99%
Usage Used in the treatment of chronic lymphocytic leukemia non-Hodgkins lymphoma and multiple myeloma
Physical Form Solid
Smell Odorless
Loss on Drying ≤0.5%
Structural Formula C1=NC2=C(C=CC(=C2)Cl)C(OC3=CC=C(C=C3)Cl)=C1Cl
Poisonous YES
Medicine Name Bendamustine hydrochloride
Solubility Freely soluble in water slightly soluble in ethanol
Color White to off-white
Type Active Pharmaceutical Ingredient (API)
Heavy Metal (%) ≤0.001%

Product Description

Bendamustine hydrochloride is a pharmaceutical-grade active pharmaceutical ingredient (API) primarily utilized in the treatment of chronic lymphocytic leukemia, non-Hodgkins lymphoma, and multiple myeloma. This bitter-tasting, odorless compound appears as a white to off-white crystalline powder. It is characterized by its high purity (99%) and stability, with a shelf life of up to 24 months when stored in a controlled environment between 15C and 30C, away from light and moisture. Bendamustine hydrochloride possesses a melting point between 153C and 156C and is freely soluble in water while slightly soluble in ethanol. Its molecular formula is C16H21Cl2N3O2.HCl, with a molecular weight of 394.72 g/mol. It maintains safety standards with loss on drying 0.5% and heavy metal content 0.001%. The API is engineered with a consistent particle size of 50100 microns, ensuring ease of handling and formulation. As a poisonous substance, handling Bendamustine hydrochloride requires strict adherence to safety guidelines to ensure its efficacy in pharmaceutical applications.

FAQs of Bendamustine hydrochloride:

Q: What type of physical form does Bendamustine hydrochloride possess?

A: Bendamustine hydrochloride is a solid, crystalline powder that appears white to off-white.

Q: How should Bendamustine hydrochloride be stored?

A: It should be stored at room temperature (15C30C) in a dry, moisture-free place protected from light.

Q: What is the shelf life of Bendamustine hydrochloride?

A: The shelf life of the product is 24 months when stored under recommended conditions.

Q: Is Bendamustine hydrochloride soluble in water?

A: Yes, it is freely soluble in water and slightly soluble in ethanol.

Q: What is the primary industrial use of Bendamustine hydrochloride?

A: It is primarily used in the pharmaceutical industry for the treatment of chronic lymphocytic leukemia, non-Hodgkins lymphoma, and multiple myeloma.

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